Second Line Agents
Information
These drugs are intended to control rheumatoid and other inflammatory
arthritides.
Aims:
- reduce morning stiffness
- reduce frequency and duration of "flare ups"
- reduce the need for NSAID's
There is some evidence to support the concept of preventing progression
or damage caused by the disease process.
These drugs cause bone marrow suppression (Hydroxychloroquine
excepted) and most cause glomerulonephritis, therefore monitoring
of blood and urine is mandatory.
- Sulphasalazine (Salazopyrin EN)
- Hydroxychloroquine (Plaquenil)
- Gold sodium aurothiomalate (Myocrisin)/auranofin (Ridaura)
- D-penecillamine (Distamine Pendramine)
- Methotrexate (Maxtrex)
- Azathioprin (Imuran)
- Cyclosporin A
- Cyclophosphamide
Document Information
Expiry Date: 11/04/04
Author: Kennedy Tom Dr
Organisation: Arrowe Park Hospital
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